Structure of PDB 8dhn Chain A

Receptor sequence
>8dhnA (length=179) Species: 641501 (Influenza A virus (A/California/04/2009(H1N1))) [Search protein sequence]
SAMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMY
SDFGHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIE
IGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRA
RIKTRLFTIRQEMASRSLWDSFRQSERGE
3D structure
PDB8dhn Carboxylic Acid Isostere Derivatives of Hydroxypyridinones as Core Scaffolds for Influenza Endonuclease Inhibitors.
ChainA
Resolution2.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 T6U A H41 E80 D108 E119 K134 E198 H43 E61 D89 E100 K115 E179
BS02 MN A H41 D108 E119 I120 H43 D89 E100 I101
BS03 MN A E80 D108 E61 D89
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8dhn, PDBe:8dhn, PDBj:8dhn
PDBsum8dhn
PubMed36655124
UniProtC3W5S0

[Back to BioLiP]