Structure of PDB 8df9 Chain A

Receptor sequence
>8df9A (length=781) Species: 2320 (Methanopyrus kandleri) [Search protein sequence]
ALVYDAEFVGSEREFEEERETFLKGVKAYDGVLATRYLMERSSSAKNDEE
LLELHQNFILLTGSYACSIDPTEDRYQNVIVRGVNFDERVQRLSTGGSPA
RYAIVYRRGWRAIAKALDIDEEDVPAIEVRAVKRNPLQPALYRILVRYGR
VDLMPVTVDEVPPEMAGEFERLIERYDVPIDEKEERILEILRENPWTPHD
EIARRLGLSVSEVEGEKDPESSGIYSLWSRVVVNIEYDERTAKRHVKRRD
RLLEELYEHLEELSERYLRHPLTRRWIVEHKRDIMRRYLEQRIVECALKL
QDRYGIREDVALCLARAFDGSISMIATTPYRTLKDVCPDLTLEEAKSVNR
TLATLIDEHGLSPDAADELIEHFESIAGILATDLEEIERMYEEGRLSEEA
YRAAVEIQLAELTKKEGVGRKTAERLLRAFGNPERVKQLAREFEIEKLAS
VEGVGERVLRSLVPGYASLISIRGIDRERAERLLKKYGGYSKVREAGVEE
LREDGLTDAQIRELKGLKTLESIVGDLEKADELKRKYGSASAVRRLPVEE
LRELGFSDDEIAEIKGIPKKLREAFDLETAAELYERYGSLKEIGRRLSYD
DLLELGATPKAAAEIKERSEEEWKEWLERKVGEGRARRLIEYFGSAGEVG
KLVENAEVSKLLEVPGIGDEAVARLVPGYKTLRDAGLTPAEAERVLKRYG
SVSKVQEGATPDELRELGLGDAKIARILGLRSLVNARLDVDTAYELARRY
GSVSAVRAAPVAELRELGLSDRAIARIAGIP
3D structure
PDB8df9 Structures of topoisomerase V in complex with DNA reveal unusual DNA binding mode and novel relaxation mechanism.
ChainA
Resolution3.24 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A G517 K519 T520 S540 A541 S542 W699 K703 S825 G516 K518 T519 S539 A540 S541 W626 K630 S752
BS02 dna A S469 Y491 P569 K570 L591 G751 K753 T754 S776 R830 S468 Y490 P568 K569 L590 G678 K680 T681 S703 R757
BS03 MG A T414 K416 T413 K415
BS04 MG A I471 I476 I470 I475
Gene Ontology
Biological Process
GO:0006281 DNA repair

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8df9, PDBe:8df9, PDBj:8df9
PDBsum8df9
PubMed35969036
UniProtQ977W1

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