Structure of PDB 8de3 Chain A

Receptor sequence
>8de3A (length=539) Species: 9823 (Sus scrofa) [Search protein sequence]
RETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFG
GIPLFYMELALGQYHRNGCISIWRKICPIFKGIGFAICVIAFYIASYYNT
IMAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNVTWMLHSTSPA
EEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTIIYFSIWKGVKTSG
KVVWVTATFPYIILSILLVRGATLPGAWRGVLFYLKPNWQKLLETGVWVD
AAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFV
IFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFF
LMLITLGLDSTFAGLEGVITAVLDEFPHFWSKRREWLALGVVITCFLGSL
ITLTFGGAYVVKLLEEFATGPAVLTVALIEAVAVFWFYGITQFCSDVKEM
LGFSPGWFWRICWVAISPLFLVFIICSFLMSPPQLWLFQYNYPQWSIILG
YCIGTSSFICIPTYITYRLIITPGTLKERIVKGITPETP
3D structure
PDB8de3 Native serotonin transporter in complex with 15B8 Fab antibody in the presence of cocaine
ChainA
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COC A Y132 D135 A206 F372 F378 S475 G479 T534 Y17 D20 A91 F257 F263 S360 G364 T419
BS02 Y01 A T159 Y395 L399 C406 T44 Y280 L284 C291
BS03 Y01 A K122 L126 Y326 S330 K7 L11 Y211 S215
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:8de3, PDBe:8de3, PDBj:8de3
PDBsum8de3
PubMed
UniProtF1RN70

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