Structure of PDB 8dbr Chain A

Receptor sequence
>8dbrA (length=508) Species: 562 (Escherichia coli) [Search protein sequence]
NSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADAMQGEMI
SLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKATGRILEVPVGRGL
LGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAV
DSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKAIYVAIGQKAS
TISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGAAMGEYFRDRG
EDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAAR
VNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQI
FLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYREL
AAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAER
GYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGI
LDSFKATQ
3D structure
PDB8dbr Changes within the central stalk of E. coli F 1 F o ATP synthase observed after addition of ATP.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.2.2: H(+)-transporting two-sector ATPase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP A R171 Q172 G174 K175 T176 A177 F360 R365 Q435 R168 Q169 G171 K172 T173 A174 F357 R362 Q432
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0032559 adenyl ribonucleotide binding
GO:0043531 ADP binding
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 proton-transporting ATPase activity, rotational mechanism
Biological Process
GO:0006754 ATP biosynthetic process
GO:0015986 proton motive force-driven ATP synthesis
GO:0042777 proton motive force-driven plasma membrane ATP synthesis
GO:0046034 ATP metabolic process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0045259 proton-transporting ATP synthase complex
GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8dbr, PDBe:8dbr, PDBj:8dbr
PDBsum8dbr
PubMed36631659
UniProtP0ABB0|ATPA_ECOLI ATP synthase subunit alpha (Gene Name=atpA)

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