Structure of PDB 8daf Chain A

Receptor sequence
>8dafA (length=230) Species: 9606 (Homo sapiens) [Search protein sequence]
PNVPELILQLLQLEPDEDQVRARILGSDQPAAFGLLCRMADQTFISIVDW
ARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQ
EVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSL
DLKFLNNHILVKDAQEKANAALLDYTLCHYPHSGDKFQQLLLCLVEVRAL
SMQAKEYLYHKHLGNEMPRNNLLIEMLQAK
3D structure
PDB8daf Comparison of activity, structure, and dynamics of SF-1 and LRH-1 complexed with small molecule modulators.
ChainA
Resolution2.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R281 Q294 M295 L451 E454 M455 R52 Q65 M66 L222 E225 M226
BS02 IUW A C266 M268 H310 L325 V326 L344 L347 C37 M39 H81 L96 V97 L115 L118
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity

View graph for
Molecular Function
External links
PDB RCSB:8daf, PDBe:8daf, PDBj:8daf
PDBsum8daf
PubMed37328104
UniProtQ13285|STF1_HUMAN Steroidogenic factor 1 (Gene Name=NR5A1)

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