Structure of PDB 8d52 Chain A

Receptor sequence
>8d52A (length=101) Species: 9606 (Homo sapiens) [Search protein sequence]
DVMTKEEQIFLLHRAQAQCEKRLKEVLQRPAGRPCLPEWDHILCWPLGAP
GEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKF
L
3D structure
PDB8d52 Parathyroid hormone 1 receptor extracellular domain complexed with a peptide ligand containing (2-naphthyl)-beta-3-homoalanine
ChainA
Resolution2.02 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A M32 K34 E35 I38 D113 H114 I115 I135 Y136 D137 F138 V157 H160 R162 T163 W164 A165 N166 Y167 F173 L174 M3 K5 E6 I9 D40 H41 I42 I62 Y63 D64 F65 V84 H87 R89 T90 W91 A92 N93 Y94 F100 L101
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8d52, PDBe:8d52, PDBj:8d52
PDBsum8d52
PubMed37587780
UniProtQ03431|PTH1R_HUMAN Parathyroid hormone/parathyroid hormone-related peptide receptor (Gene Name=PTH1R)

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