Structure of PDB 8d3l Chain A

Receptor sequence
>8d3lA (length=343) Species: 272558 (Halalkalibacterium halodurans C-125) [Search protein sequence]
MKKLLNTLYVTQPDTYLSLDGDNVVLLKEQEKLGRLPLHNLEAIVGFGYT
GASPALMGYCAERNISITFLTKNGRFLARVVGESRGNVVLRKTQYRISEN
DQESTKIARNFITGKVYNSKWMLERMTREHPLRVNVEQFKATSQLLSVMM
QEIRNCDSLESLRGWEGQAAINYNKVFDQMILQQKEEFAFHGRSRRPPKD
NVNAMLSFAYTLLANDVAAALETVGLDAYVGFMHQDRPGRASLALDLMEE
LRGLYADRFVLSLINRKEMTADGFYKKENGAVLMTDEARKTFLKAWQTKK
QEKITHPYLGEKMSWGLVPYVQALLLARFLRGDLDEYPPFLWK
3D structure
PDB8d3l PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation.
ChainA
Resolution3.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A D14 Y49 D14 Y49
BS02 dna A N73 R75 R196 F208 R289 L293 K294 N73 R75 R196 F208 R289 L293 K294
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8d3l, PDBe:8d3l, PDBj:8d3l
PDBsum8d3l
PubMed36272411
UniProtQ9KFX9

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