Structure of PDB 8d3g Chain A

Receptor sequence
>8d3gA (length=431) Species: 9606 (Homo sapiens) [Search protein sequence]
APSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSK
ELWFSDDPNVTKTLRFKQKERSIYFQPPSFYVSAQDLPHIENGGVAVLTG
KKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSR
TTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKARALGTEV
IQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLL
IKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQAR
SNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQS
MFWSDLGGYEAIGLVDSSLPTVGVFKGVIFYLRDKVVVGIVLWNIFNRMP
IARKIIKDGEQHEDLNEVAKLFNIHLEVLFQ
3D structure
PDB8d3g Integrating early structural selection into chemical library screening for drug discovery with high-throughput small-angle X-ray scattering (SAXS)
ChainA
Resolution2.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.6.99.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A G138 T141 A142 E164 D165 R172 P173 K177 K232 V233 T260 G261 F284 R285 G437 D438 H454 H455 A458 G11 T14 A15 E37 D38 R45 P46 K50 K102 V103 T130 G131 F154 R155 G307 D308 H324 H325 A328
BS02 QD1 A F310 L311 E314 H454 F482 F180 L181 E184 H324 F352
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046983 protein dimerization activity

View graph for
Molecular Function
External links
PDB RCSB:8d3g, PDBe:8d3g, PDBj:8d3g
PDBsum8d3g
PubMed38671223
UniProtO95831|AIFM1_HUMAN Apoptosis-inducing factor 1, mitochondrial (Gene Name=AIFM1)

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