Structure of PDB 8czn Chain A

Receptor sequence
>8cznA (length=186) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
YEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPE
GVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTI
RSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPA
MFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK
3D structure
PDB8czn Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PKN A Q35 L40 Q33 L38
BS02 PKN A N62 F63 M64 G66 N60 F61 M62 G64
BS03 PKN A V16 P20 A141 D144 V14 P18 A139 D142
Gene Ontology
Molecular Function
GO:0003756 protein disulfide isomerase activity
GO:0005515 protein binding
GO:0015035 protein-disulfide reductase activity
GO:0015036 disulfide oxidoreductase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0071236 cellular response to antibiotic
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space

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Cellular Component
External links
PDB RCSB:8czn, PDBe:8czn, PDBj:8czn
PDBsum8czn
PubMed36760747
UniProtP0AEG4|DSBA_ECOLI Thiol:disulfide interchange protein DsbA (Gene Name=dsbA)

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