Structure of PDB 8czf Chain A

Receptor sequence
>8czfA (length=161) Species: 9606 (Homo sapiens) [Search protein sequence]
GSMSEEQVAQDTEEVFRSYVFYRHQQEQEAAPADPEMVTLPLQPSSTMGQ
VGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGI
NWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQ
RGGWVAALNLG
3D structure
PDB8czf Peptides from human BNIP5 and PXT1 and non-native binders of pro-apoptotic BAK can directly activate or inhibit BAK-mediated membrane permeabilization.
ChainA
Resolution1.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I81 R88 Y89 F93 M96 H99 I114 S117 L118 S121 N124 G126 R127 A130 F134 I58 R65 Y66 F70 M73 H76 I91 S94 L95 S98 N101 G103 R104 A107 F111
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:8czf, PDBe:8czf, PDBj:8czf
PDBsum8czf
PubMed36706751
UniProtQ16611|BAK_HUMAN Bcl-2 homologous antagonist/killer (Gene Name=BAK1)

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