Structure of PDB 8cyo Chain A

Receptor sequence
>8cyoA (length=231) Species: 9606 (Homo sapiens) [Search protein sequence]
SLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTG
SMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKL
IFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMV
TERHGLKEPKRVEELQNKIVNTLKDHVTFNNPNYLSKLLGKLPELRTLCT
QGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF
3D structure
PDB8cyo Nurr1 Covalently Bound to a Synthetic Ligand, 10.25, via a Disulfide Bond
ChainA
Resolution2.41 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 OBJ A E440 S441 A442 F443 L444 E445 C566 I588 L591 F592 T595 E78 S79 A80 F81 L82 E83 C199 I221 L224 F225 T228
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8cyo, PDBe:8cyo, PDBj:8cyo
PDBsum8cyo
PubMed
UniProtP43354|NR4A2_HUMAN Nuclear receptor subfamily 4 group A member 2 (Gene Name=NR4A2)

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