Structure of PDB 8cxd Chain A

Receptor sequence
>8cxdA (length=188) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKL
PEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQ
TIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGV
PAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK
3D structure
PDB8cxd Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 010 A F29 Q97 Q100 F29 Q97 Q100
BS02 010 A E94 K98 E94 K98
BS03 010 A T168 M171 F174 T168 M171 F174
Gene Ontology
Molecular Function
GO:0003756 protein disulfide isomerase activity
GO:0005515 protein binding
GO:0015035 protein-disulfide reductase activity
GO:0015036 disulfide oxidoreductase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0071236 cellular response to antibiotic
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space

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Cellular Component
External links
PDB RCSB:8cxd, PDBe:8cxd, PDBj:8cxd
PDBsum8cxd
PubMed36760747
UniProtP0AEG4|DSBA_ECOLI Thiol:disulfide interchange protein DsbA (Gene Name=dsbA)

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