Structure of PDB 8cvd Chain A

Receptor sequence
>8cvdA (length=325) Species: 33113 (Atropa belladonna) [Search protein sequence]
VSESFVAPLEKRAENDVPLGNDVPIIDLQQDHLVVVQQITKACQDFGLFQ
VINHGLPEKLMAETMDVCKEFFALPAEEKEKLQPKGEPAKFELPLEQKAK
LYVEGEQEAFLYWKDTLAHGCHPLDEELVNSWPEKPATYREVVAKYSVEV
RKLTMRILDYICEGLGLKLGYFDNELSQIQMMLTNYYPPCPDPSSTLGSG
GHYDGNLITLLQQNLPGLQQLIAKWIAVEPIPTAFVVNLGLTLKVITNEK
FEGSIHRVVTNPTRDRVSIATLIGPDYSCTIEPAKELLSQDNPPLYKPYS
YAEFGEIYLSDKSDYDAGVKPYKIN
3D structure
PDB8cvd Structure of the H6H cyclization product complex
ChainA
Resolution1.717 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.14.11.11: hyoscyamine (6S)-dioxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE2 A H217 D219 H273 H202 D204 H256
BS02 OW0 A F103 E116 L198 H217 D219 G220 L289 Y318 Y325 F91 E104 L183 H202 D204 G205 L272 Y301 Y308
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0031418 L-ascorbic acid binding
GO:0046872 metal ion binding
GO:0047998 hyoscyamine (6S)-dioxygenase activity
Biological Process
GO:0002238 response to molecule of fungal origin
GO:0009805 coumarin biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8cvd, PDBe:8cvd, PDBj:8cvd
PDBsum8cvd
PubMed
UniProtQ9XJ43

[Back to BioLiP]