Structure of PDB 8cv7 Chain A

Receptor sequence
>8cv7A (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
SEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDL
STVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVF
EFRYAKMPD
3D structure
PDB8cv7 Peptide 2.2E in complex with BRD2-BD2
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A A367 W370 V376 L381 N429 H433 D434 V435 A437 M438 A21 W24 V30 L35 N83 H87 D88 V89 A91 M92
External links
PDB RCSB:8cv7, PDBe:8cv7, PDBj:8cv7
PDBsum8cv7
PubMed37269828
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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