Structure of PDB 8cv6 Chain A

Receptor sequence
>8cv6A (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
GPLGSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCD
IIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAM
ARKLQDVFEMRFAKMP
3D structure
PDB8cv6 Peptide 4.2B in complex with BRD4.2
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A W374 A384 L385 L387 N433 H437 W32 A42 L43 L45 N91 H95
External links
PDB RCSB:8cv6, PDBe:8cv6, PDBj:8cv6
PDBsum8cv6
PubMed37269828
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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