Structure of PDB 8crl Chain A

Receptor sequence
>8crlA (length=317) Species: 1639 (Listeria monocytogenes) [Search protein sequence]
HMMYFIDNNNEKDPRINLAVEEFILTELNLDEPVLLFYINKPSIIIGRNQ
NTVEEIDTEYVEKNDVIVVRRLSGGGAVYHDEGNLNFSFITEDDGESFHN
FAKFTQPIVEALKRLGVNAELKGRNDLLIDGFKVSGNAQFATKGKMFSHG
TLMYDLNLDNVAASLKRVANISDFMDQEMTTEEFRDLLLLYIFGVEKVED
VKEYKLTAADWEKIHEISAKRYGNWDWNYGKSPKFDLTRTKRFPVGAVDV
RLNVQKGVITDIKIFGDFFGVKNVADIEEKLVNTTYKREVLAEALVDIDV
KEYFGNITKDEFLDLLY
3D structure
PDB8crl A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites.
ChainA
Resolution2.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 6.3.1.20: lipoate--protein ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VK9 A I43 R69 G74 A75 V76 Y77 H78 K131 G134 N135 H147 T149 M151 I45 R71 G76 A77 V78 Y79 H80 K133 G136 N137 H149 T151 M153
BS02 CA A D328 Y331 D314 Y317
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0016979 lipoate-protein ligase activity
GO:0017118 lipoyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0009249 protein lipoylation
GO:0036211 protein modification process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8crl, PDBe:8crl, PDBj:8crl
PDBsum8crl
PubMed37249408
UniProtA0A1D2IX29

[Back to BioLiP]