Structure of PDB 8cqy Chain A

Receptor sequence
>8cqyA (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
DSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLN
EGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRR
3D structure
PDB8cqy Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A K20 F21 G22 F23 N24 L25 K26 Q31 S38 H72 D73 V76 K16 F17 G18 F19 N20 L21 K22 Q27 S34 H68 D69 V72
External links
PDB RCSB:8cqy, PDBe:8cqy, PDBj:8cqy
PDBsum8cqy
PubMed37200868
UniProtP26045|PTN3_HUMAN Tyrosine-protein phosphatase non-receptor type 3 (Gene Name=PTPN3)

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