Structure of PDB 8cqm Chain A

Receptor sequence
>8cqmA (length=221) Species: 1639 (Listeria monocytogenes) [Search protein sequence]
WDVNTHYWLFKQAEKILAKDVNHMRANLMNELKKFDKQIAQGIYDADHDT
STFLSHFYNPDRDPGFANAKITGAKYFNQSVTDYREGKFDTAFYKLGLAI
HYYTDISQPMHANNFTAISYPPGYHSAYENYVDTIKHNYQATEDMVAKRF
SSDDVKDWLYENAKRAKADYPKIVNAKTKKSYLVGNSEWKKDTVEPTGAR
LRDSQQTLAGFLEFWSKKTNE
3D structure
PDB8cqm Structural basis for the unique molecular properties of broad-range phospholipase C from Listeria monocytogenes.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.4.3: phospholipase C.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H69 H118 D122 H56 H101 D105
BS02 FE A H128 H142 E146 H111 H125 E129
BS03 FE A W1 H14 D122 W1 H6 D105
Gene Ontology
Molecular Function
GO:0004629 phospholipase C activity
GO:0004767 sphingomyelin phosphodiesterase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0034480 phosphatidylcholine phospholipase C activity
GO:0046872 metal ion binding
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:8cqm, PDBe:8cqm, PDBj:8cqm
PDBsum8cqm
PubMed37838694
UniProtP33378|PHLC_LISMO Phospholipase C (Gene Name=plcB)

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