Structure of PDB 8coh Chain A

Receptor sequence

>8cohA (length=132) Species: 9844 (Lama glama) [Search protein sequence]

EVQLVESGGGLVQPGGSLRLSCAASGRAHSDYAMAWFRQAPGQEREFVAG
IGWSGGDTLYADSVRGRFTNSRDNSKNTLYLQMNSLRAEDTAVYYCAARQ
GQYIYSSMRSDSYDYWGQGTLVTVSSHHHHHH

3D structure

PDB

8coh Characterization of the bispecific VHH antibody gefurulimab (ALXN1720) targeting complement component 5, and designed for low volume subcutaneous administration.

Chain

Resolution

1.3 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MN	A	H127 H129	H127 H129

External links

PDB	RCSB:8coh, PDBe:8coh, PDBj:8coh
PDBsum	8coh
PubMed	38142486

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