Structure of PDB 8cmi Chain A

Receptor sequence
>8cmiA (length=183) Species: 9606 (Homo sapiens) [Search protein sequence]
MIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFG
RFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVEL
REPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFH
YLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDA
3D structure
PDB8cmi Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q9 S53 F54 G58 N62 V65 N69 I72 R76 Q10 S54 F55 G59 N63 V66 N70 I73 R77
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8cmi, PDBe:8cmi, PDBj:8cmi
PDBsum8cmi
PubMed37471227
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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