Structure of PDB 8cls Chain A

Receptor sequence
>8clsA (length=837) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
PTMRLSQNVKPCKSMDIRNMVSHFNQLENCTVIEGFLLIDLINDASPLNR
SFPKLTEVTDYIIIYRVTGLHSLSKIFPNLSVIRGNKLFDGYALVVYSNF
DLMDLGLHKLRSITRGGVRIEKNHKLCYDRTIDWLEILAENETQLVVLTE
NGKEKQLHNNRRLCWNSKLCQTKCPEKCRNNCIDEHTCCSQDCLGGCVID
KNGNESCISCRNVSFNNICMDSCPKGYYQFDSRCVTANECITLTKFETNS
VYSGIPYNGQCITHCPTGYQKSENKRMCEPCPGGKCDKECSSGLIDSLER
AREFHGCTIITGTEPLTISIKRESGAHVMDELKYGLAAVHKIQSSLMVHL
TYGLKSLKFFQSLTEISGDPPMDADKYALYVLDNRDLDELWGPNQTVFIR
KGGVFFHFNPKLCVSTINQLLPMLASKPKFFEKSDVGADSNGNRGSCGTA
VLNVTLQSVGANSAMLNVTTKVEIGEPQKPSNATIVFKDPRAFIGFVFYH
MIDPYGNSTKSSDDPCDDRWKVSSPEKSGVMVLSNLIPYTNYSYYVRTMA
ISSELTNAESDVKNFRTNPGRPSKVTEVVATAISDSKINVTWSYLDKPYG
VLTRYFIKAKLINRPTRNNNRDYCTEPLGMEFENALQNFIFVPNKDDENT
YKDEEDLSSNKQFYEVFAKELPPNQTHFVFEKLRHFTRYAIFVVACREEI
PSEKLRDTSFKKSLCSDYDTVFQTTKRKKFADIVMDLKVDLEHANNTESP
VRVRWTPPVDPNGEIVTYEVAYKLQKPDQVEEKKCIPAADFNQTAGYLIK
LNEGLYSFRVRANSIAGYGDFTEVEHIKVEPPPSYAK
3D structure
PDB8cls Structural conservation of insulin/IGF signalling axis at the insulin receptors level in Drosophila and humans.
ChainA
Resolution4.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
Interaction with ligand
External links
PDB RCSB:8cls, PDBe:8cls, PDBj:8cls
PDBsum8cls
PubMed37805602
UniProtP09208|INSR_DROME Insulin-like receptor (Gene Name=InR)

[Back to BioLiP]