Structure of PDB 8ck5 Chain A

Receptor sequence
>8ck5A (length=239) Species: 7955 (Danio rerio) [Search protein sequence]
HMLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRRLSMLPHLADLVS
YSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMS
WSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMA
ICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKL
ADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEV
3D structure
PDB8ck5 Structural analysis and biological activities of C25-amino and C25-nitro vitamin D analogs.
ChainA
Resolution2.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I270 K274 R280 I288 K292 P442 E446 E451 V452 I57 K61 R67 I75 K79 P229 E233 E238 V239
BS02 UYO A Y175 L258 A259 V262 S265 R302 S303 S306 W314 V328 H333 Y22 L45 A46 V49 S52 R89 S90 S93 W101 V115 H120
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8ck5, PDBe:8ck5, PDBj:8ck5
PDBsum8ck5
PubMed37054528
UniProtQ9PTN2|VDRA_DANRE Vitamin D3 receptor A (Gene Name=vdra)

[Back to BioLiP]