Structure of PDB 8ciw Chain A

Receptor sequence

>8ciwA (length=555) Species: 78543 (Pseudomonas migulae)

MLPITAADDVQGLLLQLRGLLEQAISALASRCTKGRQLDAELLDLMQVPT
FELAWASAELLAAERSLQAIDAGTSSVDRRLILVFAVEAITLVHSRLEAI
YAELDLADGTLHAIAADQKLRALRRSVLSSTALHDSARLMVERPEQIGQV
AMGDELSMIEDQFRRFAADTVAPLAEHIHREDLIIPDSLLAALRDMGVFG
LSIPERYGGSAPDDQEDPLTMIVVTEALSQASLAAAGSLITRPEILSRAL
LSGGTESQKQHWLARLAVGDPLCAIAITEPDYGSDVAGLTLRGTPCEGGW
RLNGAKTWCTFAGKAGVLMVVTRTNPDKSLGHRGLSLLLAEKPSYDGHEF
DFRQPGGGSLTGRAIPTIGYRGMHSFDLSFEDFFVPDGNVIGEAQGLGKG
FYHTMAGMTGGRMQTAGRASGVMRAALLAGLRYATERKVFGSPLLDYPLT
GAKLTKMAARYVASRYLTYSVGRMLAQGEGRMEASLVKLFACRSAELVTR
ESLQIHGGMGYAEEVAVSRYFVDARVLSIFEGAEETLALKVIGRSLLEAA
LKAEA

3D structure

• PDB: 8ciw Exploring alternative pathways for the in vitro establishment of the HOPAC cycle for synthetic CO 2 fixation.
• Chain: A
• Resolution: 1.93 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	Q47 I275 I277 T278 G283 S284 W308 T310 F530 E535 T536	Q47 I275 I277 T278 G283 S284 W308 T310 F530 E535 T536
BS02	ZKK	A	R242 S284 V286 H332 Y370 F401 Y402 M405 M408 R412 R418 F530 E531 G532 R544	R242 S284 V286 H332 Y370 F401 Y402 M405 M408 R412 R418 F530 E531 G532 R544
BS03	FAD	A	R437 V439 F440 L444 Q504 I505 G508	R437 V439 F440 L444 Q504 I505 G508

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0003995 acyl-CoA dehydrogenase activity
• GO:0016491 oxidoreductase activity
• GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
• GO:0050660 flavin adenine dinucleotide binding

External links

• PDB: RCSB:8ciw, PDBe:8ciw, PDBj:8ciw
• PDBsum: 8ciw
• PubMed: 37315145
• UniProt: A0A1H5ILA2