Structure of PDB 8cis Chain A

Receptor sequence
>8cisA (length=312) Species: 9606 (Homo sapiens) [Search protein sequence]
PKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQD
TKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRL
FFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDK
LLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMY
GVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFN
DKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIE
VQQMKAQAREEK
3D structure
PDB8cis The FERM domain of human moesin with two bound peptides identified by phage display
ChainA
Resolution1.52 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K27 F30 W43 L61 N62 K83 F84 E289 L290 K26 F29 W42 L60 N61 K82 F83 E288 L289
BS02 peptide A W242 N247 I248 F250 N251 D252 L274 K278 L281 H288 W241 N246 I247 F249 N250 D251 L273 K277 L280 H287
BS03 peptide A A14 E15 L16 E17 A13 E14 L15 E16
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0008092 cytoskeletal protein binding
Cellular Component
GO:0005856 cytoskeleton

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8cis, PDBe:8cis, PDBj:8cis
PDBsum8cis
PubMed37866628
UniProtP26038|MOES_HUMAN Moesin (Gene Name=MSN)

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