Structure of PDB 8ccn Chain A

Receptor sequence
>8ccnA (length=372) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
AVALVVDNGSGMVKSGLAGDDAPKCVFPSIVGRPKMPNIMIGMEQKECYV
GDEAQNKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVSPEEHPVL
LTEAPLNPKTNREKMTQIMFETFDVPAMYVSIQAILSLYASGRTTGIVLD
SGDGVSHTVPIYEGYVLPHAINRIDMAGRDLTYHMMKLFTERGHTFTTTA
EREIVRDIKEKLCYIAMDYDEELKRSEEHSDEIEEIYELPDGNLITVGSE
RFRCPEALFNPTLIGRECPGLHITAYQSIMKCDIDIRKELYNNIVLSGGT
TMYNNIGERLTKEMTNLAPSSMKIKVIAPPERKYSVWIGGSILSSLSTFQ
QMWITKEEYEDSGPSIVHRKCF
3D structure
PDB8ccn Structure and function of Plasmodium actin II in the parasite mosquito stages.
ChainA
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A G13 M16 D157 K213 E214 G303 M306 Y307 G9 M12 D153 K209 E210 G299 M302 Y303
Gene Ontology
Molecular Function
GO:0000146 microfilament motor activity
GO:0005200 structural constituent of cytoskeleton
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:0007010 cytoskeleton organization
GO:0070360 symbiont-mediated actin polymerization-dependent cell-to-cell migration in host
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005884 actin filament

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ccn, PDBe:8ccn, PDBj:8ccn
PDBsum8ccn
PubMed36877739
UniProtQ8ILW9|ACT2_PLAF7 Actin-2 (Gene Name=ACT2)

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