Structure of PDB 8ccd Chain A

Receptor sequence
>8ccdA (length=128) Species: 9606 (Homo sapiens) [Search protein sequence]
GAPATVTEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLS
NGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEIAHLLIKPEYA
YGSAGSLPKIPSNATLFFEIELLDFKGE
3D structure
PDB8ccd Structure-Based Discovery of a New Selectivity-Enabling Motif for the FK506-Binding Protein 51.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UCO A Y57 K60 L61 D68 F77 G84 Q85 V86 I87 W90 Y113 I122 F130 Y45 K48 L49 D56 F65 G72 Q73 V74 I75 W78 Y101 I110 F118
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity

View graph for
Molecular Function
External links
PDB RCSB:8ccd, PDBe:8ccd, PDBj:8ccd
PDBsum8ccd
PubMed37058391
UniProtQ13451|FKBP5_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP5 (Gene Name=FKBP5)

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