Structure of PDB 8cao Chain A

Receptor sequence
>8caoA (length=255) Species: 142864 (Cylindrospermum stagnale) [Search protein sequence]
GSEPTFVVNASLLPSKVLGLQVQRPQSFNYQPGDYLFIKCPGISKFEWHP
FTISSAPEMPDVLTLHIRAVGSWTGKLYQLIREQREEWIRSGSSQSLPGV
PVYIDGPYGTPSTHIFESKYAILICAGIGVTPFASILKSILHRNQQNPAK
MPLKKVHFYWLNREQKAFEWFVELLSKIEAEDTNNLFDLNLYLTLITGLK
SRTKTGRPDWEEIFKDVAKQHAPDNVEVFFCGPTGLALQLRHLCTKYGFG
YRKEN
3D structure
PDB8cao Targeting ROS through the discovery of isoform-selective NADPH oxidase inhibitors
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A Y445 H459 P460 F461 T462 H476 I477 V480 G481 S482 W483 T484 I538 Y35 H49 P50 F51 T52 H66 I67 V70 G71 S72 W73 T74 I128
BS02 U40 A T462 A536 G537 I538 G539 C668 P670 E691 T52 A126 G127 I128 G129 C231 P233 E254
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:8cao, PDBe:8cao, PDBj:8cao
PDBsum8cao
PubMed37884805
UniProtK9WT99

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