Structure of PDB 8c9s Chain A

Receptor sequence
>8c9sA (length=223) Species: 227882 (Streptomyces avermitilis MA-4680 = NBRC 14893) [Search protein sequence]
SESQQLWDDVDDYFTTLLAPEDEALTAALRDSDAAGLPHINVAPNQGKLL
QLLAEIQGARRILEIGTLGGYSTIWLGRALPRDGRLISFEYDAKHAEVAR
RNLARAGLDGISEVRVGPALESLPKLADERPEPFDLVFIDADKVNNPHYV
EWALKLTRPGSLIVVDNVVRGGGVTDAGSTDPSVRGTRSALELIAEHPKL
SGTAVQTVGSKGYDGFALARVLP
3D structure
PDB8c9s Structural Characterization and Extended Substrate Scope Analysis of Two Mg 2+ -Dependent O-Methyltransferases from Bacteria.
ChainA
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A I41 N42 V43 G67 L69 S73 E91 Y92 H96 P119 A120 D141 A142 D143 I40 N41 V42 G66 L68 S72 E90 Y91 H95 P118 A119 D140 A141 D142
BS02 MG A D141 D167 N168 D140 D166 N167
BS03 BAQ A Q47 L51 D167 F217 Q46 L50 D166 F216
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008171 O-methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0032259 methylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8c9s, PDBe:8c9s, PDBj:8c9s
PDBsum8c9s
PubMed36942619
UniProtQ82B68

[Back to BioLiP]