Structure of PDB 8c73 Chain A

Receptor sequence
>8c73A (length=195) Species: 274 (Thermus thermophilus) [Search protein sequence]
EDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEA
WHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIG
AMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLR
ALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALW
3D structure
PDB8c73 Redox driven B 12 -ligand switch drives CarH photoresponse.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 B12 A L121 L124 R125 G128 E141 S145 R176 H177 E178 I179 G180 S222 L225 G247 G248 Q249 M264 D266 L267 L41 L44 R45 G48 E61 S65 R96 H97 E98 I99 G100 S142 L145 G167 G168 Q169 M184 D186 L187
Gene Ontology
Molecular Function
GO:0031419 cobalamin binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8c73, PDBe:8c73, PDBj:8c73
PDBsum8c73
PubMed37604813
UniProtQ53W62|CARH_THET8 HTH-type transcriptional repressor CarH (Gene Name=carH)

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