Structure of PDB 8c4r Chain A

Receptor sequence
>8c4rA (length=153) Species: 1639 (Listeria monocytogenes) [Search protein sequence]
SRIEREQHHLIESIEKSTQYMAKRRIGALISVARDTGMDDYIETGIPLNA
KISSQLLINIFIPNTPLHDGAVIIKGNEIASAASYLPLSDSPFLSKELGT
RHRAALGISEVTDSITIVVSEETGGISLTKGGELFRDVSEEELHKILLKE
LVT
3D structure
PDB8c4r Computer-aided design of a cyclic di-AMP synthesizing enzyme CdaA inhibitor.
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.85: diadenylate cyclase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADE A L88 L90 T102 L86 L88 T100
Gene Ontology
Molecular Function
GO:0004016 adenylate cyclase activity
Biological Process
GO:0006171 cAMP biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8c4r, PDBe:8c4r, PDBj:8c4r
PDBsum8c4r
PubMed37223749
UniProtQ8Y5E4|DACA_LISMO Diadenylate cyclase (Gene Name=dacA)

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