Structure of PDB 8c4n Chain A

Receptor sequence
>8c4nA (length=152) Species: 1639 (Listeria monocytogenes) [Search protein sequence]
RIEREQHHLIESIEKSTQYMAKRRIGALISVARDTGMDDYIETGIPLNAK
ISSQLLINIFIPNTPLHDGAVIIKGNEIASAASYLPLSDSPFLSKELGTR
HRAALGISEVTDSITIVVSEETGGISLTKGGELFRDVSEEELHKILLKEL
VT
3D structure
PDB8c4n Computer-aided design of a cyclic di-AMP synthesizing enzyme CdaA inhibitor.
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.85: diadenylate cyclase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A L31 D71 G72 Y87 L88 T102 L28 D68 G69 Y84 L85 T99
Gene Ontology
Molecular Function
GO:0004016 adenylate cyclase activity
Biological Process
GO:0006171 cAMP biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8c4n, PDBe:8c4n, PDBj:8c4n
PDBsum8c4n
PubMed37223749
UniProtQ8Y5E4|DACA_LISMO Diadenylate cyclase (Gene Name=dacA)

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