Structure of PDB 8c45 Chain A

Receptor sequence
>8c45A (length=1218) Species: 568708 (Salmonella enterica subsp. enterica serovar Typhimurium str. D23580) [Search protein sequence]
MNTNNIKKYAPQARNQFRDAVIQKLTTLGISADKKGNLQIADAELVGETM
RYYPKSTLTRRDRLVKRAREQGFDVLVEHCAYTWFNRLCAIRYMEIHGYL
DHGFHMLSHPDNPTGFEVLDHVPEVAEALLPEKKAQLVEMKLSGNQDEAI
YRELLLAQCHALHRAMPFLFEAVDDEAELLLPDNLTRTDSILRGLVDGIP
EEDWQEVEVIGWLYQFYISEKKDAVIGKVVKSEDIPAATQLFTPNWIVQY
LVQNSVGRQWLQTYPDSPLKGKMDYYIEPAEQTPEVQAQLAAITPASIEP
ESIKVLDPACGSGHILIEVYNVLKNIYEERGYRARDIPQLILENNIFGLD
IDDRAAQLSGFALLMMARQDDRRIFTRDVRLNIVSLQESLHLDIAKLWQQ
LNFHQQNQTGSMGAENTALAHTDSAEYQLLMRTLKRFVNAKTLGSLIQVP
QEEEAELKAFLEALYRMEQEGDFQQKAAAKAFIPYIQQAWILAQRYDAVV
ANPPYMGGKGMNSELKEFAKNNFPDSKADLFAMFMQNAFSLLKENGFNAQ
VNMQSWMFLSSYEALRNWLLDNKTFITMAHLGARAFGQISGEVVQTTAWV
IKNQHSERYQPVFFRLIDGREEVKKSDLLLRKNIFDKFTQHDFKNIPGMP
IAYWIDLPSLLSFRHHKKLGEKIALKAGMSTGDNIKFQRYWYEVSIKKTL
ITNKESNTKIDIHNIKWFPCSSGGEYRKWYGNNEIVVNWENNGYEIRNFK
FENGKTRSAVRNDEYYFREGITWSKISQGNFCVRYRPKGFVFDDTGRCGF
SNNKNELLYAAGLMCTPVVNHYLSILAPTLSFTSGELASVPYPEIEDEII
ELVTNAIEIAKNDWDSQEQSWDYVCSPLLEHNSTQLLRNIYKQKINTNIK
LVETLLLIENTINNIFIDKLQLDKTIIKAVLQSEITLLCNPNYRYKNIQD
HTDLTNKYYTDITIDILSYIIGCMMGRYSLDREGLVYAHEGNKGFAELVA
EDAYKTFPADNDGILPLMDDEWFDDDVTSRVKEFVRTVWGEEHLQENLEF
IAESLCLYAIKPKKGESALDTIRRYLSTQFWKDHMKMYKKRPIYWLFSSG
KEKAFECLVYLHRYNDATLARMRTEYVVPLLARYQANIDRLNEQVDGASG
GEATRLKRERDSLSKKFNELRSFDDRLRHYADMRISIDLDDGVKVNYGKF
GDLLADVKAITGNAPEII
3D structure
PDB8c45 Phage defence protein
ChainA
Resolution3.5 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SAM A Y218 T243 Q244 F246 T247 A313 C314 D354 I355 N509 P511 F541 Y214 T239 Q240 F242 T243 A309 C310 D350 I351 N502 P504 F534
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
Biological Process
GO:0032259 methylation

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8c45, PDBe:8c45, PDBj:8c45
PDBsum8c45
PubMed39174540
UniProtA0A6C7IK61

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