Structure of PDB 8c1u Chain A

Receptor sequence
>8c1uA (length=500) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
RSTLVHWFRKGLRLHDNPALSHIFTAANAAPGRYFVRPIFILDPGILDWM
QVGANRWRFLQQTLEDLDNQLRKLNSRLFVVRGKPAEVFPRIFKSWRVEM
LTFETDIEPYSVTRDAAVQKLAKAEGVRVETHCSHTIYNPELVIAKNLGK
APITYQKFLGIVEQLKVPKVLGVPEKLKNMPTPPKDEVEQKDSAAYDCPT
MKQLVKRPEELGPNKFPGGETEALRRMEESLKDEIWVARFEKPNTAPNSL
EPSTTVLSPYLKFGCLSARLFNQKLKEIIKRQPKHSQPPVSLIGQLMWRE
FYYTVAAAEPNFDRMLGNVYCMQIPWQEHPDHLEAWTHGRTGYPFIDAIM
RQLRQEGWIHHLARHAVACFLTRGDLWISWEEGQRVFEQLLLDQDWALNA
GNWMWLSASAFFHQYFRVYSPVAFGKKTDPQGHYIRKYVPELSKYPAGCI
YEPWKASLVDQRAYGCVLGTDYPHRIVKHEVVHKENIKRMGAAYKVNREV
3D structure
PDB8c1u Femtosecond serial crystallography resolves conformational changes which guide long-range electron transfer in a photolyase
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FAD A K246 T258 T259 V260 L261 S262 L265 Q299 W302 R303 Y306 W362 H365 R368 F391 D397 D399 L402 N403 N406 W407 K242 T254 T255 V256 L257 S258 L261 Q295 W298 R299 Y302 W358 H361 R364 F387 D393 D395 L398 N399 N402 W403
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003904 deoxyribodipyrimidine photo-lyase activity
GO:0071949 FAD binding
Biological Process
GO:0032922 circadian regulation of gene expression
GO:0043153 entrainment of circadian clock by photoperiod
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8c1u, PDBe:8c1u, PDBj:8c1u
PDBsum8c1u
PubMed38225270
UniProtQ8SXK5

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