Structure of PDB 8c17 Chain A

Receptor sequence
>8c17A (length=220) Species: 9606 (Homo sapiens) [Search protein sequence]
GPRSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQSSPSYSDPYLEA
VDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNIEDEGSSFY
GVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRS
PLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYV
FEVSASEHGAQHHIYRLVKE
3D structure
PDB8c17 Biochemical and Structural Characterization of a Peptidic Inhibitor of the YAP:TEAD Interaction That Binds to the alpha-Helix Pocket on TEAD.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A S336 F337 V341 Y369 F373 K376 L377 L380 S388 V389 N392 F393 S122 F123 V127 Y155 F159 K162 L163 L166 S174 V175 N178 F179
External links
PDB RCSB:8c17, PDBe:8c17, PDBj:8c17
PDBsum8c17
PubMed36825662
UniProtQ15561|TEAD4_HUMAN Transcriptional enhancer factor TEF-3 (Gene Name=TEAD4)

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