Structure of PDB 8bx1 Chain A

Receptor sequence
>8bx1A (length=127) Species: 10090 (Mus musculus) [Search protein sequence]
GAMDMKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTI
SRFEALQLSLKNMSKLRPLLEKWVEEADNNRVRWSLETMFLKSPKPSLQQ
ITHIANQLGLEKDVVRVWFSNRRQKGK
3D structure
PDB8bx1 Crystal structure of Oct4-Soc2-HoxB1 complex
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A S43 T45 T46 R49 S56 N59 Q146 S46 T48 T49 R52 S59 N62 Q124
BS02 dna A R20 T26 Q27 Q44 S48 V139 N143 R23 T29 Q30 Q47 S51 V117 N121
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8bx1, PDBe:8bx1, PDBj:8bx1
PDBsum8bx1
PubMed
UniProtP20263|PO5F1_MOUSE POU domain, class 5, transcription factor 1 (Gene Name=Pou5f1)

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