Structure of PDB 8bvq Chain A

Receptor sequence

>8bvqA (length=785) Species: 562 (Escherichia coli)

FVVKDIHFEGLQRVAVGAALLSMPVRTGDTVNDEDISNTIRALFATGNFE
DVRVLRDGDTLLVQVKERPTIASITFSGNKSVKDDMLKQNLEASGVRVGE
SLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPRNRVDLKLVFQEGV
SAEIQQINIVGNHAFTTDELISHFQLRDEVPWWNVVGDRKYQKQKLAGDL
ETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEV
SGNLAGHSAEIEQLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQ
SMPEINDADKTVKLRVNVDAGNRFYVRKIRFEGNDTSKDAVLRREMRQME
GAWLGSDLVDQGKERLNRLGFFETVDTDTQRVPGSPDQVDVVYKVKERNT
GSFNFGIGYGTESGVSFQAGVQQDNWLGTGYAVGINGTKNDYQTYAELSV
TNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKSYGTDVTLGFPINEYN
SLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFKTDDFTFN
YGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDD
DHKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAV
YFPHQASNYDPDYDYECATQDGAKDLCKSDDAVGGNAMAVASLEFITPTP
FISDKYANSVRTSFFWDMGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIA
LQWMSPLGPLVFSYAQPFKKYDGDKAEQFQFNIGK

3D structure

• PDB: 8bvq Darobactin B Stabilises a Lateral-Closed Conformation of the BAM Complex in E. coli Cells.
• Chain: A
• Resolution: 3.3 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	R421 N422 G424 S425 F426 N427 F428 I430 L780 K808	R398 N399 G401 S402 F403 N404 F405 I407 L757 K785

Gene Ontology

Molecular Function

• GO:0005515 protein binding

Biological Process

• GO:0007155 cell adhesion
• GO:0043165 Gram-negative-bacterium-type cell outer membrane assembly
• GO:0051205 protein insertion into membrane
• GO:0071709 membrane assembly

Cellular Component

• GO:0009279 cell outer membrane
• GO:0016020 membrane
• GO:0019867 outer membrane
• GO:1990063 Bam protein complex

External links

• PDB: RCSB:8bvq, PDBe:8bvq, PDBj:8bvq
• PDBsum: 8bvq
• PubMed: 37162386
• UniProt: P0A940|BAMA_ECOLI Outer membrane protein assembly factor BamA (Gene Name=bamA)