Structure of PDB 8bv1 Chain A

Receptor sequence
>8bv1A (length=155) Species: 9606 (Homo sapiens) [Search protein sequence]
MAKVQVNNVVVLDNPSPFYNPFQFEITFECIEDLSEDLEWKIIYVGSAES
EEYDQVLDSVLVGPVPAGRHMFVFQADAPNPGLIPDADAVGVTVVLITCT
YRGQEFIRVGYYVNNEYTETELRENPPVKPDFSKLQRNILASNPRVTRFH
INWED
3D structure
PDB8bv1 Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
ChainA
Resolution2.834 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A A48 E51 D54 D88 V92 V94 R108 Y112 R145 A48 E51 D54 D88 V92 V94 R108 Y112 R145
BS02 peptide A I31 E32 D33 I31 E32 D33
BS03 peptide A S35 E36 D37 P64 P66 S35 E36 D37 P64 P66
Gene Ontology
Biological Process
GO:0006325 chromatin organization
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:8bv1, PDBe:8bv1, PDBj:8bv1
PDBsum8bv1
PubMed37347155
UniProtQ9Y294|ASF1A_HUMAN Histone chaperone ASF1A (Gene Name=ASF1A)

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