Structure of PDB 8btl Chain A

Receptor sequence
>8btlA (length=354) Species: 9606 (Homo sapiens) [Search protein sequence]
LIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEELENKPRKQQGYST
VSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPE
SAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTG
GGGRESNIHLIPYIIHTVLYVLNTTRATSREEKNLQGFLEQPKEKWVESA
FEVDGPYYFTVLALHILPPEQWRATRVEILRRLLVTSQARAVAPGGATRL
TDKAVKDYSAYRSSLLFWALVDLIYNMFKKVPTSNTEGGWSCSLAEYIRH
NDMPIYEAADKALKTFQEEFMPVETFSEFLDVAGLLSEITDPESFLKDLL
NSVP
3D structure
PDB8btl An Atypical E3 Ligase Module in UBR4 Mediates Destabilization of N-degron Substrates
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C4838 H4887 C4890 C9 H58 C61
External links
PDB RCSB:8btl, PDBe:8btl, PDBj:8btl
PDBsum8btl
PubMed38182926
UniProtQ5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 (Gene Name=UBR4)

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