Structure of PDB 8br9 Chain A

Receptor sequence
>8br9A (length=212) Species: 2261 (Pyrococcus furiosus) [Search protein sequence]
IGRISTGSKSLDKLLGGGIETQAITEVFGEFGSGKTQLAHTLAVMVQLPP
EEGGLNGSAMYIDTENTFRPERLREIAQNRGLDPDEVLDNVAYARAFNSN
HQMQLLYQASAMMVESLNTDRPYKLLIVDSLTSHFRSEYIGRGALAERQQ
KLARFLRMLHRLANEFDIAVFVTNQTLRVYLRKGKRIARLIDAPHLPEGE
AVFSITEKGIED
3D structure
PDB8br9 A Recombinant Approach For Stapled Peptide Discovery Yields Inhibitors of the RAD51 Recombinase
ChainA
Resolution1.63 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A L197 D198 V200 A201 Y202 A203 H210 L214 Y216 Q217 S219 M221 M267 R270 L271 L88 D89 V91 A92 Y93 A94 H101 L105 Y107 Q108 S110 M112 M158 R161 L162
BS02 ADP A F140 G141 G143 K144 T145 Q146 R181 I342 F31 G32 G34 K35 T36 Q37 R72 I205
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016887 ATP hydrolysis activity
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0006259 DNA metabolic process
GO:0006281 DNA repair
GO:0006310 DNA recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:8br9, PDBe:8br9, PDBj:8br9
PDBsum8br9
PubMed38075664
UniProtO74036|RADA_PYRFU DNA repair and recombination protein RadA (Gene Name=radA)

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