Structure of PDB 8bpq Chain A

Receptor sequence
>8bpqA (length=362) Species: 562 (Escherichia coli) [Search protein sequence]
EKLYSPLKVGAITAANRIFMAPLTRLRSIEPGDIPTPLMAEYYRQRASAG
LIISEATQISAQAKGYAGAPGIHSPEQIAAWKKITAGVHAENGHMAVQLW
HTGRISHASLQPGGQAPVAPSALSAGTRTSLRDENGQAIRVETSMPRALE
LEEIPGIVNDFRQAIANAREAGFDLVELHSAHGFLLHQFLSPSSNHRTDQ
YGGSVENRARLVLEVVDAGIEEWGADRIGIRVSPIGTFQNTDNGPNEEAD
ALYLIEQLGKRGIAYLHMSEPDWAGGEPYTDAFREKVRARFHGPIIGAGA
YTVEKAETLIGKGLIDAVAFGRDWIANPDLVARLQRKAELNPQRAESFYG
GGAEGYTDYPTL
3D structure
PDB8bpq Development of the Biocatalytic Reductive Aldol Reaction
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMN A P25 L26 T27 A59 Q101 H182 H185 R234 W276 G302 F323 G324 R325 Y352 P22 L23 T24 A56 Q98 H179 H182 R231 W273 G299 F320 G321 R322 Y349
BS02 7MT A Y69 R143 W276 F351 Y352 Y66 R140 W273 F348 Y349
Gene Ontology
Molecular Function
GO:0008748 N-ethylmaleimide reductase activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0034567 chromate reductase activity
GO:0046857 oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor
Biological Process
GO:0006805 xenobiotic metabolic process
GO:0018937 nitroglycerin metabolic process
GO:0046256 2,4,6-trinitrotoluene catabolic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8bpq, PDBe:8bpq, PDBj:8bpq
PDBsum8bpq
PubMed
UniProtP77258|NEMA_ECOLI N-ethylmaleimide reductase (Gene Name=nemA)

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