Structure of PDB 8bpl Chain A

Receptor sequence
>8bplA (length=316) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence]
SPLQEMLAAPSSFKKSHVLSVTQFTRADLHLLFQIAQEMRLGVQREGVLD
ILRGKVLCTLFYEPSTRTSASFDAAMQRLGGRTIPIQTSTSSVQKGETLQ
DTLRTLACYSDAIVLRHPDEKCVDVAKKYCPVPVINGGNGSKEHPTQAFL
DLFTIREELGTMQGLTITFVGDLLYGRPVHSLVYLLRHYQVKVQLVSPKA
LRLPPAVRQQLVDAGQLLCESEALTPEILGRTDVLYCTRVQKERFPSLAE
FEAVKDSYRIDYSTLKYAKPTTVVMHPLPRNEEVAEEVDFDQRAAYFRQM
CYGLYCRMALLALVMS
3D structure
PDB8bpl A Tailored Strategy to Crosslink the Aspartate Transcarbamoylase Domain of the Multienzymatic Protein CAD.
ChainA
Resolution1.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.3.2: aspartate carbamoyltransferase.
3.5.1.2: glutaminase.
6.3.4.16: carbamoyl-phosphate synthase (ammonia).
6.3.5.5: carbamoyl-phosphate synthase (glutamine-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CP A S2002 T2003 R2004 T2005 R2053 H2081 Q2084 L2215 S65 T66 R67 T68 R116 H144 Q147 L278
Gene Ontology
Molecular Function
GO:0004070 aspartate carbamoyltransferase activity
GO:0016597 amino acid binding
GO:0016743 carboxyl- or carbamoyltransferase activity
Biological Process
GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006520 amino acid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8bpl, PDBe:8bpl, PDBj:8bpl
PDBsum8bpl
PubMed36677714
UniProtG0S583

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