Structure of PDB 8baj Chain A

Receptor sequence
>8bajA (length=127) Species: 9606 (Homo sapiens) [Search protein sequence]
GAPATVTEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLS
NSKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEIAHLLIKPEYA
YGSAGSLPKIPSNATLFFEIELLDFKG
3D structure
PDB8baj Binding pocket stabilization by high-throughput screening of yeast display libraries.
ChainA
Resolution1.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 9QN A Y47 F57 D58 F67 V76 I77 W80 Y103 S108 K111 F120 Y45 F55 D56 F65 V74 I75 W78 Y101 S106 K109 F118
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity

View graph for
Molecular Function
External links
PDB RCSB:8baj, PDBe:8baj, PDBj:8baj
PDBsum8baj
PubMed36419931
UniProtQ13451|FKBP5_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP5 (Gene Name=FKBP5)

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