Structure of PDB 8b5c Chain A

Receptor sequence
>8b5cA (length=126) Species: 9606 (Homo sapiens) [Search protein sequence]
SHMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAV
KLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYN
KPGDDIVLMAEALEKLFLQKINELPT
3D structure
PDB8b5c Synthesis, Biochemical Characterization, and Genetic Encoding of a 1,2,4-Triazole Amino Acid as an Acetyllysine Mimic for Bromodomains of the BET Family.
ChainA
Resolution1.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F79 W81 F83 L92 L94 D96 I100 I138 Y139 N140 D145 M149 F39 W41 F43 L52 L54 D56 I60 I98 Y99 N100 D105 M109
External links
PDB RCSB:8b5c, PDBe:8b5c, PDBj:8b5c
PDBsum8b5c
PubMed36585954
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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