Structure of PDB 8b23 Chain A

Receptor sequence
>8b23A (length=702) Species: 2336 (Thermotoga maritima) [Search protein sequence]
YVAALFFLIPLVALGFAAANFAAVVRKPEGTERMKEISSYIRSGADSFLA
HETKAIFKVAIVIAILLMIFTTWQTGVAFLLGAVMSASAGIVGMKMATRA
NVRVAEAARTTKKIGPALKVAYQGGSVMGLSVGGFALLGLVLVYLIFGKW
MGQVDNLNIYTNWLGINFVPFAMTVSGYALGCSIIAMFDRVGGGVYTKAA
DMAADLVGKTELNLPEDDPRNPATIADNVGDNVGDVAGLGADLLESFVGA
IVSSIILASYMFPIYVQKIGENLVHQVPKETIQALISYPIFFALVGLGCS
MLGILYVIVKKPSDNPQRELNISLWTSALLTVVLTAFLTYFYLKDLQGLD
VLGFRFGAISPWFSAIIGIFSGILIGFWAEYYTSYRYKPTQFLGKSSITG
MVISNGLSLGMKSVFPPTLTLVLGILFADYFAGLYGVAIAALGMLSFVAT
SVSVDSYGPIADNAGGISEMCELDPEVRKITDHLDAVGNTTAAIGKGFAI
GSAIFAALSLFASYMFSQISPSDIGKPPSLVLLLNMLDARVIAGALLGAA
ITYYFSGYLISAVTKAAMKMDYNRCIEITSDNALKQMGYPAFIAILTPLV
TGFLLGAEFVGGVLIGTVLSGAMLAILTANSGGAWDNAKKYLEAGNLEGY
GKGSEPHKALVIGDTVGDPLKDTVGPSLDILIKIMSVVSVIAVSIFKHVH
LF
3D structure
PDB8b23 Towards automated crystallographic structure refinement with phenix.refine.
ChainA
Resolution3.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.2.3.1: Na(+)-exporting diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D202 D228 D201 D227
BS02 MG A D232 D465 D231 D462
BS03 MG A K199 D202 D692 K198 D201 D668
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004427 inorganic diphosphate phosphatase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0009678 diphosphate hydrolysis-driven proton transmembrane transporter activity
GO:0015081 sodium ion transmembrane transporter activity
GO:0030955 potassium ion binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006814 sodium ion transport
GO:0035725 sodium ion transmembrane transport
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8b23, PDBe:8b23, PDBj:8b23
PDBsum8b23
PubMed38182815
UniProtQ9S5X0|HPPA_THEMA K(+)-stimulated pyrophosphate-energized sodium pump (Gene Name=hppA)

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