Structure of PDB 8b1w Chain A

Receptor sequence
>8b1wA (length=231) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
ETGDQRFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLVV
DTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIAT
YANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGH
TSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAA
FPKASMIVMSHSAPDSRAAITHTARMADKLR
3D structure
PDB8b1w Structural characterization of triazole-based inhibitors of metallo-beta-lactamases
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H120 H122 H189 H81 H83 H150
BS02 ZN A D124 C208 H250 D85 C169 H211
BS03 CA A E152 D223 E113 D184
BS04 CA A D95 D130 D56 D91
BS05 OQU A W93 H189 K211 G219 N220 H250 W54 H150 K172 G180 N181 H211
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0017001 antibiotic catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8b1w, PDBe:8b1w, PDBj:8b1w
PDBsum8b1w
PubMed38139809
UniProtF6IAY7

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