Structure of PDB 8ayy Chain A

Receptor sequence
>8ayyA (length=235) Species: 12086 (Poliovirus 3) [Search protein sequence]
QRRSRSESTIESFFARGACVAIIEVDNEEPTTRAQKLFAMWRITYKDTVQ
LRRKLEFFTYSRFDMELTFVVTANFTNTNNGHALNQVYQIMYIPPGAPTP
KSWDDYTWQTSSNPSIFYTYGAAPARISVPYVGLANAYSHFYDGFAKVPL
KTDANDQIGDSLYSAMTVDDFGVLAIRVVNDHNPTKVTSKVRIYMKPKHV
RVWCPRPPRAVPYYGPGVDYKDNLNPLSEKGLTTY
3D structure
PDB8ayy A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 W11 A I108 M130 L132 Y157 I181 Y203 F236 I43 M65 L67 Y92 I116 Y138 F171
BS02 GSH A I87 R257 I22 R192
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:8ayy, PDBe:8ayy, PDBj:8ayy
PDBsum8ayy
PubMed36434067
UniProtQ84895

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