Structure of PDB 8ayx Chain A

Receptor sequence
>8ayxA (length=235) Species: 12086 (Poliovirus 3) [Search protein sequence]
QRRSRSESTIESFFARGACVAIIEVDNEEPTTRAQKLFAMWRITYKDTVQ
LRRKLEFFTYSRFDMELTFVVTANFTNTNNGHALNQVYQIMYIPPGAPTP
KSWDDYTWQTSSNPSIFYTYGAAPARISVPYVGLANAYSHFYDGFAKVPL
KTDANDQIGDSLYSAMTVDDFGVLAIRVVNDHNPTKVTSKVRIYMKPKHV
RVWCPRPPRAVPYYGPGVDYKDNLNPLSEKGLTTY
3D structure
PDB8ayx A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YM2 A Y110 K111 M130 L132 Y157 P179 S180 I192 V194 Y203 F236 Y45 K46 M65 L67 Y92 P114 S115 I127 V129 Y138 F171
BS02 GSH A I87 R257 I22 R192
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:8ayx, PDBe:8ayx, PDBj:8ayx
PDBsum8ayx
PubMed36434067
UniProtQ84895

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