Structure of PDB 8ayr Chain A

Receptor sequence
>8ayrA (length=677) Species: 239935 (Akkermansia muciniphila) [Search protein sequence]
GCLTPLKPVPSAEQLEWHDMEMYAFVHFTINTFTGKEWGYGDEKPELFHP
SDFDADDLVRTLADAGFKGVVLTCKHHDGFCLWPTKTTLHSVAASPWKQG
KGDVVKEVSRACGKYGVRFGVYLSPWDRNAASYGTPDYIRMYRQQLKELA
TGYGSIFLAWFDGANGGDGYYGGARERRSIDRSAYYDWKATWGELKKRQP
GAVIFSDVGPDVRWVGNESGYAGYPCWATYTPVPLQAGTEPAPGTVRYRL
GTEGTMDGKYWIPAEVDVSIRPGWFWHEHENSRVRTPENLLKLYFDSVGR
GANLNLNVPPDRRGRIHEEDKKSLAGFRVLLDELYSRNFASGAQAESSSS
WKGHGAEQVLDRKRTTYWVAAPEDKHPCVVLKLPEPAAFDVIRLAEPIQL
GQRVRKFRVEVRENGQWSKWTEGASIGARVLLKGRPVTADGVRVVLEQSR
AVPALCEVSLWKYPVILNAPAVNYDRNGRVTLASAENVVIRYTTDGTEPG
PQSAMYRNPFFLPAGGTVKAAAEYRGRKSSVTTQIIPVPTRDWKVVAGER
SAAAPELAIDGDSSTLWHTHAAQGELAPPQALEIDMGRPVNVAAVIYTPR
RDSSTGTVDRYAVYLSMDGNTWGAPAAEGEFSNIRANPVPQRIDLKAPVK
ARYLRFVGKRVVEGSHVAVAELGVLGK
3D structure
PDB8ayr Sialidases and fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A Q386 D389 K391 T394 C484 Q358 D361 K363 T366 C456
BS02 CA A L585 D588 D590 T593 A698 E699 L557 D560 D562 T565 A670 E671
Gene Ontology
Molecular Function
GO:0004560 alpha-L-fucosidase activity
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8ayr, PDBe:8ayr, PDBj:8ayr
PDBsum8ayr
PubMed37005422
UniProtB2UQE4

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