Structure of PDB 8ay4 Chain A

Receptor sequence
>8ay4A (length=269) Species: 12130 (rhinovirus A2) [Search protein sequence]
LVVPNINSSNPTTSNSAPALDAAETGHTSSVQPEDVIETRYVQTSQTRDE
MSLESFLGRSGCIHESKLEVTLANYNKENFTVWAINLQEMAQIRRKFELF
TYTRFDSEITLVPCISALSQDIGHITMQYMYVPPGAPVPNSRDDYAWQSG
TNASVFWQHGQAYPRFSLPFLSVASAYYMFYDGYDEQDQNYGTANTNNMG
SLCSRIVTEKHIHKVHIMTRIYHKAKHVKAWCPRPPRALEYTRAHRTNFK
IEDRSIQTAIVTRPIITTA
3D structure
PDB8ay4 Endosome rupture enables enteroviruses to infect cells.
ChainA
Resolution4.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D49 E54 D106 S167 K226 H227 D49 E54 D106 S167 K226 H227
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:8ay4, PDBe:8ay4, PDBj:8ay4
PDBsum8ay4
PubMed
UniProtP04936|POLG_HRV2 Genome polyprotein

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