Structure of PDB 8aw7 Chain A

Receptor sequence
>8aw7A (length=309) Species: 1639 (Listeria monocytogenes) [Search protein sequence]
KKVGLLVMAYGTPYKDEDIERYYTDIRHGHKPSEEMIADLRGLYHAIGGL
SPLAKITEAQAYGLEKALNDSQDEVEFKAYIGLKHIEPFIEDAVEAMHKD
GIEEAISIVLAPHYSSFSVEAYNKRAKEAADKLGGPRINAINDWYKQPKF
IQMWADRINETAKQIPADELLDTVLIVSAHSLPEKIKQHNDPYPNQLQET
ADFIFEKVVVPHYALGWQSEGKTGEPWLGPDVQDLTRELYGREKYKHFIY
TPVGFVAEHLEVLYDNDYECKVVTDEVGAAYHRPPMPNSDPEFLEVLRTV
VWEKYSNLE
3D structure
PDB8aw7 Active site architecture of coproporphyrin ferrochelatase with its physiological substrate coproporphyrin III: Propionate interactions and porphyrin core deformation.
ChainA
Resolution2.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.99.1.9: coproporphyrin ferrochelatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HT9 A Y12 T14 Y25 I28 Y46 S53 L55 Y124 H182 H261 L262 E263 Y10 T12 Y23 I26 Y44 S51 L53 Y122 H180 H259 L260 E261
Gene Ontology
Molecular Function
GO:0004325 ferrochelatase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0006783 heme biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8aw7, PDBe:8aw7, PDBj:8aw7
PDBsum8aw7
PubMed36479958
UniProtQ8Y565|CPFC_LISMO Coproporphyrin III ferrochelatase (Gene Name=cpfC)

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